A Simple Protocol for Platelet-mediated Clumping of <em>Plasmodium falciparum</em>-infected Erythrocytes in a Resource Poor Setting
نویسندگان
چکیده
منابع مشابه
A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
P. falciparum causes the majority of severe malarial infections. The pathophysiological mechanisms underlying cerebral malaria (CM) are not fully understood and several hypotheses have been put forward, including mechanical obstruction of microvessels by P. falciparum-parasitized red blood cells (pRBC). Indeed, during the intra-erythrocytic stage of its life cycle, P. falciparum has the unique ...
متن کاملPlatelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
Sequestration of malaria-infected erythrocytes in the peripheral circulation has been associated with the virulence of Plasmodium falciparum. Defining the adhesive phenotypes of infected erythrocytes may therefore help us to understand how severe disease is caused and how to prevent or treat it. We have previously shown that malaria-infected erythrocytes may form apparent autoagglutinates of in...
متن کاملDyspepsia Management in a Resource Poor Setting
BACKGROUND Dyspepsia has a significant impact on the quality of life of the sufferer, and results in enormous societal costs, either due to direct medical costs for physician visits, diagnostic tests, medications, or indirect costs from absenteeism or reduced productivity at work. It is therefore important to explore the management options available, especially in a resource poor setting like N...
متن کاملSurvival of Extremely Preterm Neonates in a Resource-limited Setting
Background: Preterm birth is a major contributor to neonatal and under-five mortality, and births at lower gestational ages (GA) contribute more to these statistics. Most developed countries have succeeded in improving survival at extremes of GA, while most developing countries like Nigeria still lag behind. The objective of this retrospective study was to document the...
متن کاملPhotographic assessment of burn wounds: a simple strategy in a resource-poor setting.
OBJECTIVE To validate the use of photographic burn wound assessment in evaluation of burn size and wound characteristics. METHODS Feasibility study of agreement between methods of measurement of burn size and characteristics, in patients admitted to the burn unit at Kamuzu Central Hospital (KCH), Malawi, over two months in 2011. Burn wounds were photographed and assessed clinically, concurren...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2013
ISSN: 1940-087X
DOI: 10.3791/4316